Effects of hyperbaric oxygen treatment on implant osseointegration in experimental diabetes mellitus

Abstract Objective To evaluate whether hyperbaric oxygen (HBO) treatment has a favorable effect on implant osseointegration in diabetic rabbits. Material and Methods An experimental diabetes model was induced in 32 New Zealand rabbits through IV injection of alloxan. After the state of diabetes had been confirmed, one dental implant was placed in the metaphysical region of each animal's tibia. After the implants' placements, the animals were divided into two groups. Half of the animals underwent HBO treatment, while the other group did not receive HBO treatment and served as the control group. The animals were euthanized at the 4th and 8th weeks. The osseointegration of the implants were compared by histomorphometry and resonance frequency analysis (RFA). Results The Bone Implant Contact (BIC) values were significantly higher in the HBO group than in the control group at the 4th week. There was no difference in the BIC values between the groups at the 8th week. There was no significant difference in the RFA scores between the groups both at the 4th and 8th weeks after the operation. Conclusion Histomorphometry findings suggest that HBO has positive effect on implant osseointegration in the early healing period in diabetic rabbits. However, implant stability is not affected by HBO treatment.

Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs

To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. METHODS: Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals were sacrificed on the 12th postoperative week and the tibial bones were removed, histologic sections were prepared and the experimental sites were examined microscopically and stereologically. RESULTS: Histologic and stereologic examination revealed more new bone formation in the defects filled with PRF mixed β-TCP than in the defects grafted with either β-TCP or PRF alone. CONCLUSION: The platelet rich fibrin and beta tricalcium phosphate combination effectively induces new bone formation.

Evaluation of articular eminence morphology and inclination in TMJ internal derangement patients with MRI / Evaluación de la morfología e inclinación de la eminencia articular en pacientes con trastorno interno de ATM con MRI

Articular eminence morphology and inclination are reported to be two predisposing factors for the internal derangement (ID). The purpose of this study is to investigate the relationship between the inclination and morphology of the articular eminence and ID. The study included 70 temporomandibular joints with ID in 35 patients: 51 joints had disc displacements with reduction (DDWR) and 19 joints had disc displacements without reduction (DDWOR). All subjects underwent bilateral high resolution magnetic resonance imaging scans which were performed in the sagittal and coronal planes with mouths closed and opened. Articular eminence morphology was characterized as box, sigmoid, flattened, or deformed. Articular eminence inclination was measured at three positions: steep (from 60° to 90°), moderate (from 30° to 60°) and shallow (from 15° to 30°). The images were divided into two; DDWR and DDWOR, and these two criteria were compared. The images of the two groups were compared; while flattened form was occurred with the highest incidence in the DDWOR group, sigmoid form was the most frequent in the DDWR group and articular eminence inclination was found steeper than it was for the DDWOR group. The steepness of the articular eminence may not have a predisposing effect on the development of disc displacements.

La morfología e inclinación de la eminencia articular son reportados como dos factores predisponentes para el trastorno interno (TI). El propósito de este estudio fue investigar la relación entre la inclinación y la morfología de la eminencia articular y el TI. El estudio incluyó a 70 articulaciones temporomandibulares, con TI en 35 pacientes: 51 articulaciones con desplazamiento discal con reducción (DDCR) y 19 de las articulaciones tuvieron desplazamiento discal sin reducción (DDSR). Todos los sujetos fueron sometidos a imágenes de resonancia magnética bilaterales de alta resolución que se realizaron en los planos sagital y coronal con la boca cerrada y abierta. La morfología articular la eminencia se caracterizó como una caja, sigmoide, aplanada, o deforme. La inclinación de la eminencia articular se midió en tres posiciones: empinada (de 60 ° a 90 °), moderada (entre 30 ° a 60 °) y poco profunda (entre 15 ° y 30 °). Las imágenes fueron divididos en dos; DDCR y DDSOR, y estos criterios fueron comparados. Al comparar las imágenes de ambos grupos, la forma aplanada se observó con mayor incidencia en el grupo de DDSR, la forma sigmoide fue la más frecuente en el grupo de DDCR y la inclinación de la eminencia articular se encontró más pronunciada que en el grupo DDSR. La inclinación de la eminencia articular puede no tener un efecto predisponente en el desarrollo de los desplazamientos de disco.

Clinico-radiographic examination of odontogenic myxoma with displacement of unerupted upper third molar: review of the literature / Examen clínico-radiográfico de un mixoma odontogénico con desplazamiento de un tercer molar no erupcionado: revisión de la literatura

Odotogenic myxoma is a benign tumor which presents in 3 percent to 6 percent of all odontogenic tumors. According to the WHO classification, multiple radiolucent areas of varying size, separated by straight or curved bony septa with poorly defined borders are the radiologic characteristics of the condition. We report the case of maxillary odontogenic myxoma in a 21 year old man. The radiological feature of the current case was interesting, due to the size of the lesion and severe displacement of the upper third molar.

El mixoma odontogénico es un tumor benigno que se presenta en el 3 por ciento a 6 por ciento de todos los tumores odontogénicos. De acuerdo a la clasificación de la OMS, las características radiológicas de esta patología presentan múltiples áreas radiolúcidas de tamaño variable, separadas por tabiques óseos rectos o curvos, con márgenes mal definidos. Presentamos un caso de mixoma odontogénico maxilar en un hombre de 21 años. La característica radiológica es interesante, debido al tamaño de la lesión y al desplazamiento severo del tercer molar superior.